To summarize the nursing experience of a patient with multiple endocrine neoplasia catecholamine cardiomyopathy with sudden cardiac arrest. Key points of nursing care：setting up a multidisciplinary team to formulate diagnosis and treatment plan;reducing stimulation,avoiding inducing hypertensive crisis;recognition and emergency nursing care of catecholamine cardiomyopathy crisis;nursing care of extracorporeal membrane oxygenation and blood purification life support;target temperature management. The patient’s condition was stable on the 15th day of admission and she was successfully transferred to another department for further treatment.